MMAF
                                                            
                                    
                                    
                                    
                                    
                                    
                                        Key Features and
                                                Details
                                        
                                                                                            - Tubulin polymerization inhibitor
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                                                    731.96                                                
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                                                    C39H65N5O8                                                
 
                                 
                            
                         
                     
                    
                                                    
                                
                                    
                                    
                                        | Product Overview | 
                                    
                                    
                                                                                
                                                | Activity | Tubulin polymerization inhibitor | 
                                                                                    
                                                | Description | MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A. | 
                                                                            
                                
                             
                                                    
                                
                                    
                                    
                                        | Product Details | 
                                    
                                    
                                                                                
                                                | Product Name | MMAF | 
                                                                                    
                                                | CAS. No. | 745017-94-1 | 
                                                                                    
                                                | Molecular Formula | C39H65N5O8 | 
                                                                                    
                                                | Purity | >99% | 
                                                                                    
                                                | Molecular Weight | 731.96 | 
                                                                                    
                                                | SMILES | CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C)=O)C(C)C)=O | 
                                                                            
                                
                             
                                                    
                                             
                    For research use only. Not intended for any clinical use.