Cat#: CCR-0034
Perfluoro-1-butanesulfonyl fluoride
Synonyms (s): NfF, Nonafluorobutanesulfonyl fluoride
Empirical Formula (Hill Notation): C4F10O2S
Size: 25 mg; 100 mg
Product Introduction
| Molecular Weight | 302.09 |
| NACRES | NA.22 |
| CAS Number | 375-72-4 |
| MDL Number | MFCD00007422 |
| PubChem Substance ID | 24859184 |
| Assay | 96% |
| Form | Liquid |
| Reaction Suitability | Reaction type: click chemistry |
| Smiles String | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)S(F)(=O)=O |
| InChI | 1S/C4F10O2S/c5-1(6,3(9,10)11)2(7,8)4(12,13)17(14,15)16 |
| InChI key | LUYQYZLEHLTPBH-UHFFFAOYSA-N |
Application
Perfluoro-1-butanesulfonyl fluoride (NfF) reacts with alcohols, including phenols, to yield nonafluorobutanesulfonate esters (nonaflates). Nonaflates can be used as electrophiles in several palladium-catalyzed cross coupling reactions and in Buchwald-Hartwig amination.NfF can also be used to prepare aryl nonaflates by reacting with corresponding aryloxysilanes in the presence of fluoride ion.
Safety Information
| Signal Word | Danger |
| Hazard Classifications | H314 |
| Storage Class Code | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
For research use only. Not for clinical use.
