Cat#: CLP-0037
Dibenzocyclooctyne-PEG4-maleimide
Synonyms (s): DBCO-PEG4-maleimide
Empirical Formula (Hill Notation): C36H42N4O9
Size: 1 mg; 5 mg; 50 mg
Product Introduction
| Molecular Weight | 674.74 |
| NACRES | NA.22 |
| MDL Number | MFCD22572659 |
| PubChem Substance ID | 329766888 |
| Form | Solid |
| Reaction Suitability | Reaction type: Click chemistry; Reagent type: Cross-linking reagent |
| Smiles String | O=C(CCNC(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4 |
| InChI | 1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41) |
| InChI key | VVFZXPZWVJMYPX-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules. Applications Include: Protein-peptide conjugatesAntibody-enzyme or antibody-drug conjugatesProtein or peptide-oligonucleotide conjugatesSurface modification
Safety Information
| Storage Class Code | 13 - Non Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
