Cat#: CLP-0075
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Synonyms (s): 6-Maleimidocaproic acid N-succinimidyl ester,N/-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS
Empirical Formula (Hill Notation): C14H16N2O6
Size: 500 mg
Product Introduction
| Molecular Weight | 308.29 |
| NACRES | NA.22 |
| CAS Number | 55750-63-5 |
| MDL Number | MFCD00043043 |
| PubChem Substance ID | 24880215 |
| Assay | ≥95% (Oligomer uniformity) |
| Reaction Suitability | Reagent type: Cross-linking reagent |
| Smiles String | O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O |
| InChI | 1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2 |
| InChI key | VLARLSIGSPVYHX-UHFFFAOYSA-N |
| Storage Temp. | -20 °C |
Application
6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.
Safety Information
| Signal Word | Warning |
| Target Organs | Respiratory system |
| Hazard Classifications | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
