Cat#: CLP-0103
4-(N-Maleimido)benzophenone
Synonyms (s): Benzophenone-4-maleimide
Empirical Formula (Hill Notation): C17H11NO3
Size: 100 mg
Product Introduction
| Molecular Weight | 277.27 |
| NACRES | NA.22 |
| CAS Number | 92944-71-3 |
| MDL Number | MFCD00079465 |
| PubChem Substance ID | 57654429 |
| Reaction Suitability | Reagent type: Cross-linking reagent |
| Smiles String | O=C1C=CC(=O)N1c2ccc(cc2)C(=O)c3ccccc3 |
| InChI | 1S/C17H11NO3/c19-15-10-11-16(20)18(15)14-8-6-13(7-9-14)17(21)12-4-2-1-3-5-12/h1-11H |
| InChI key | OZIZEXQRIOURIJ-UHFFFAOYSA-N |
| Storage Temp. | 2-8 °C |
Application
A heterobifunctional cross-linking reagent containing a sulfhydryl-specific group and a photo-active group. Typically, coupled initially by thioether to molecule containing free sulfhydryl buffered at pH 6.8 (6.5-7.0). Second bonding occurs during UV irradiation (250 nm) via diradical excited state. Benzophenones demonstrate greater specificity for C-H insertion and are more stable in water than analogous reagents. In general they are more efficient in attachment because they may be repeatedly irradiated; however, a more intense irradiation may be required. The benzophenone is not sensitive to reduction compared to analogous reagents.
Safety Information
| Signal Word | Warning |
| Target Organs | Respiratory system |
| Hazard Classifications | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Storage Class Code | 11 - Combustible Solids |
| WGK | WGK 3 |
For research use only. Not for clinical use.
