3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

Synonyms (s): Bromo sulfonyl fluoride TMS-alkyne, Probe building block

Empirical Formula (Hill Notation): C₁₁H₁₂BrFO₂SSi

Size: 50 mg

Product Introduction

Molecular Weight	335.26
CAS Number	2088829-15-4
Assay	≥95%
Form	Powder or Crystals
Reaction Suitability	Reaction type: click chemistry
Storage Temp.	-20 °C

Application

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Safety Information

Storage Class Code	12 - Non Combustible Liquids
WGK	WGK 3

For research use only. Not for clinical use.