Centrosomal mRNA Isolation Services

During the study of centrosomal mRNA, its isolation is the first and the key step. A high-quality mRNA isolation is the basis for following analysis. CD BioSciences offers high-quality and professional centrosomal mRNA isolation and purification service from animal tissues and cultured animal cells for research use. With advanced technology, equipment, and experienced scientists, we have assisted our global customers in the field of centrosome research.

Introduction into Centrosomal mRNA

Centrosome is a cytoplasmic organelle composed of two microtubule-based cylinders called centrioles, which plays role as the main microtube organizing center (MTOC) in animal cells. The components of centrosome contain ordered matrix of proteins and mRNAs called pericentriolar material (PCM). RNAs localized on centrosome contribute a lot to changes in PCM abundance. Cell cycle-dependent PCM composition changes contribute much to the functional changes in the activity of centrosome. During mitotic, centrosome augment the capacity of microtubule-nucleating by recruiting additional PCM. And the process is reversed upon mitotic exit by PCM shedding. The composition and organization of PCMs are associated with developmental disorders, increased genomic instability, and cancer. Therefor launching transcriptome analysis are very important in understanding the composition, function and interaction of PCMs. As the first step, isolation and purification of centrosomal mRNAs appears particularly vital in centrosomal research.

Our Services

For assisting our customers all over the world making better progress in centrosomal research, CD BioSciences provides centrosomal mRNAs isolation and purification services in cells and tissues including but not limited as follows.

• Human tissue: tumor tissues, nerve cells, and other tissue of pathological changes.
• Mouse tissue: early embryos, spermatogonium, oocytes, tumor tissue, nerve cells, and other tissues and cells.
• Cell lines: Hela cells, 3T3 cells, A549 cells, HEK 293 cells, Jurkat cells, OK cells, Ptk2 cells, Vero cells and others.
• Xenopus laevis: early embryos, spermatogonium, oocytes, eggs, and many other tissues and cells.
• Drosophila: early embryos, tissues and individuals.
• Caenorhabditis elegans: embryos and individuals.
• Plant tissue: leaves, stem, root, flower, pollen, pistil, and cultured plant tissues.

Process for Centrosomal mRNA Isolation

For assisting our global customers making better progress in centrosome-related studies, CD BioSciences offers high-quality centrosomal mRNA insolation service that will be performed as below.

• Cells/Tissue harvest: cells or tissues can be provided by the customer, or CD BioSciences offers full coverage of biological experimental materials.
• Cytoplast extract: cytoplast will be extracted by our experienced scientists with high-quality.
• Centrosome polymerization: centrosome polymerization will be induced by taxol.
• Centrosomal sedimentation: with the centrifuge, centrosome will be sedimented through a glycerol cushion.
• Centrosomal mRNA purification: the centrosomal mRNA will be purified with magnetic beads.

Why Choose Us

Professional Team

Comprehensive Platform

High Efficiency

One-stop Service

With skilled and experienced genomics and cytology experts, state-of-the-art equipment and advanced technology, CD BioSciences offers customer all over the word services related to fields of centrosomal research. Our one-stop service program is your best assistant to accelerate you process of centrosomal research. Please feel free to contact us and get started with our high-quality services.

Our services are for research use only and not for any clinical use.